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Anti-estrogen-based endocrine therapies, such as the ER modulator Tamoxifen, ER degrader Fulvestrant, and the aromatase inhibitor Letrozole, have significantly enhanced the survival rates of patients with hormone receptor-positive (HR+) breast cancer [5]

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It is recommended that the sequence should contain 20% charged residues to increase its solubility

doi:10.1038/s12276-019-0355-7 Laurens C, Bourlier V, Mairal A, et al