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Description

The cytosolic GST enzymes comprise the largest family and based upon amino acid sequences and substrate specificities this family has been divided into seven subclasses identified as alpha (, A), mu (, M), omega (, O), pi (, P), sigma (, S), theta (, T), and zeta (, Z)

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Finally, with an understanding of cellular events subsequent to NAPQI, the rationale for potential therapies like fomepizole that may prevent or attenuate hepatocyte death long after NAPQI formation will be addressed

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