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The symptoms of SIBO result from excessive bacteria in the small intestine interfering with normal digestion and nutrient absorption

The peptide further counteracts gastric endothelial injury

Venneti S, Dunphy MP, Zhang H, Pitter KL, Zanzonico P, Campos C, Carlin SD, La Rocca G, Lyashchenko S, Ploessl K, Rohle D, Omuro AM, Cross JR, Brennan CW, Weber WA, Holland EC, Mellinghoff IK, Kung HF, Lewis JS, Thompson CB

Within this system, microbial signalling to epithelial cells modulates tight junction proteins, thereby regulating gut permeability to permit nutrient absorption while preventing pathogen translocation