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Not all free radicals are evil
A: The most direct and potent method is Intravenous (IV) administration, as it achieves 100% bioavailability
Moreover, natural antioxidants such as carotenoids and polyphenolic compounds can also inhibit the generation of ROS
Although direct chromatin-level regulation of flavonoid structural genes remains poorly understood, current evidence suggests that repeated stress exposure may progressively modify the inducibility of flavonoid biosynthetic pathways through epigenetic reprogramming
On the other hand, transporter-mediated Asn uptake, such as that mediated by SLC6A14, has been reported to regulate inflammatory transcription through mechanisms including histone phosphorylation and to suppress the tendency toward M1-like polarization (68)
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