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Mar 3 2011;364(9):818-828
Sulfite may also be oxidized to sulfate, extra- and intracellularly by peroxidases or non-enzymatically catalyzed by metal ions or superoxide radicals and subsequently reduced and assimilated again
A preclinical study done in a mouse model of ALS (wobbler mice) showed that treatment with an ultra-high dose of methylcobalamin inhibits disease progression
Timing: Animal protocols used both fasted and fed administration
This stacking approach requires careful timing and dose management
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