Vitamin B12 is no different
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A randomized, double-blind, controlled trial evaluating the effect of intranasal insulin on neurocognitive function in euthymic patients with bipolar disorder: intranasal insulin in bipolar disorder
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Untreated obesity increases the risk of cardiovascular disease, type 2 diabetes, obstructive sleep apnea, metabolic-associated steatotic liver disease (fatty liver), chronic kidney disease, multiple cancers (endometrial, esophageal, liver, kidney, breast), osteoarthritis, and dementia