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207 In addition, a large study that followed 2,968 subjects with cardiovascular disease for a median of almost 10 years found lower B 6 levels and higher homocysteine levels were each associated with increased mortality, higher levels of oxidative stress and inflammatory markers, and shorter telomere length for age, suggesting accelerated biological aging

As of 2016, adult obesity was associated with $260.6 billion in aggregate medical costs in the United States.[40] Looking ahead, the 2025 Joint Economic Report estimates that obesity will generate between $8.2 trillion and $9.1 trillion in excess medical expenditures over the next decadeif America fails to foster an environment in which medical innovation can effectively address obesity.[41] While employer-sponsored insurance bears the majority of obesity-related costs, Medicare and Medicaid still account for roughly 25 percent of the national burden.[42] This is particularly concerning given the high prevalence of obesity-related chronic conditions among program beneficiaries

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