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Aardvark Therapeutics Sector: Oral gut-restricted bitter taste receptor agonists for hunger suppression HQ: San Diego, CA Year Founded: 2017 Origin Story: Aardvark Therapeutics was founded around a mechanistically distinct hypothesis: rather than suppressing appetite like GLP-1 drugs, the companys lead compound activates bitter taste receptors (TAS2Rs) confined to the gastrointestinal tract to trigger local release of satiety hormones, targeting hunger itself without systemic drug exposure

This transparent model removes cost barriers to finding your optimal therapeutic doseyour dose may need to go up over 816 weeks, but your price stays the same

Make sure it is out of sight and reach of children and pets

At higher concentrations, G3 response were not good as compared to G2 concentration