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Many posts described using smaller doses, including semaglutide microdosing, as a way to manage side effects, extend medication supply, or navigate access barriers
Pernicious anaemia, atrophic gastritis, proton pump inhibitors, metformin, and gastrointestinal surgery significantly impair B12 absorption
But receiving insurance coverage doesnt always mean youll get the drug for free
This report did report an almost two-fold increase in risk for discontinuation of endoscopy (risk ratio 1.99, 95%CI 1.562.53) (Raven et al
Half-life & frequency rationale Cagrilintide has a long plasma half-life reported at roughly 7-8 days (approximately 159-195 hours across studied doses), which is the basis for once-weekly dosing in trials
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