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CLINICAL TRIAL EVIDENCE FOR DUAL GLP-1/GLUCAGON RAs AND TRIPLE AGONISTS IN MASH Survodutide Survodutide, a weekly dual GLP-1/GCG agonist, was assessed in a phase 2 dose-finding trial (NCT04771273) including 293 individuals with histologically confirmed MASH and fibrosis stages F1-F3 [46]
Among patients with prediabetes, a proportion in both populations were modelled to experience prediabetes reversal within the first 4 weeks of treatment based on data from the NMA, which included the SURMOUNT-1, SCALE and STEP 1 trials and used the treatment regimen estimand [11, 25]
I haven't experienced any side effects other maybe not craving water as much as i used to but i still drink as much as i can per day
In research settings, it is used to examine how these two receptor systems work together and how combined receptor activity influences broader metabolic and endocrine signaling