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There should also be a priority to investigate whether RT has differential effects on males and females as it relates to cerebrovascular and brain healthas sexual dimorphism in exercise-related reduction in ADRD risk remains poorly understood

PMID: 16513172 Silvagno, F., Vernone, A., Pescarmona, G.P

Starting both simultaneously may increase early tolerability challenges, which is why staggered introductionbeginning one medication, allowing adjustment, then adding the secondoften proves more practical

Importantly, ferroptosis has been proven to be a common intervention target for halting DKD progression (187)

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