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Eli Lilly highlighted that it has committed over $16 billion to develop new manufacturing sites in the US and Europe since 2020, including in a biologic facility in Limerick, Ireland

doi: 10.1016/S0140-6736(78)92994-X 6 DiakogiannakiEGribbleFMReimannF

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The timeline reflects how lipid changes unfold: triglycerides drop first (often within 8 weeks), LDL cholesterol declines more gradually (1220 weeks), and HDL increases modestly throughout