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While insulin glargine primarily reduced fasting glucose levels and actually increased body weight, exenatide decreased fed glucose levels and body weight while also reducing risk of nocturnal hypoglycemia [44]
As the hepatic T4 to T3 conversion is stimulated in response to feeding 16 , the role of hepatic TH signaling in the metabolic response to nutrient ingestion has been of interest
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Epidemiological data confirms this overlap
N Engl J Med 2025;393:10771087 (OASIS 4)
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