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Preclinical studies using STZ-induced diabetes, db/db mice, or high-fat dietSTZ combination models provide important proof-of-concept that exercise can attenuate retinal inflammation, oxidative stress, vascular leakage, and neurodegeneration (263, 264)

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Some people notice changes within hours, while others see the full effect build over several weekly sessions

A doctor may recommend vitamin B12 shots for people at risk of a deficiency or its complications, particularly if they are unable to take oral supplements