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Cancer Res 60 : 40534057

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Compelling evidence from landmark clinical trials, particularly STEP-HFpEF, STEP-HFpEF DM and SUMMIT, has established the efficacy of GLP-1RAs in improving HF-related symptoms and quality of life, as well as reducing worsening HF events, in the prevalent phenotype of HFpEF in the setting of obesity and T2D

Symptoms of Vitamin B12 deficiency include fatigue, weakness, constipation, loss of appetite, and weight loss

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