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This is the same cost-effectiveness barrier that has kept all obesity medications off provincial formularies since orlistat in the early 2000s
Ozempic (semaglutide) and Mounjaro (tirzepatide) are FDA-approved for type 2 diabetes management but may be prescribed off-label for weight management at a clinician's discretion
Traditional benefits are no longer enough to differentiate or inspire long-term loyalty
FDA Approval and Pregnancy Categories Explained The FDA is responsible for assessing and approving medications in the U.S
the AP-centric DVC atlas from Ludwig et al
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