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If SCoV2 is targeting GSH biosynthesis as well as TXNRD1 and GPx1 for proteolytic knockdown, in infected cells, the resulting decreases in these critical antioxidant molecules would contribute to increased oxidative stress, NF-B activation and pro-apoptotic signaling (17, 18)

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Due to the peculiarities of the expression location of GPX2, it is considered the first barrier for mammals to prevent the absorption of hydroperoxides produced by food.Studies have found that the expression level of selenoprotein in mammals is not balanced with the supply of selenium

Isolation of a mixed disulphide of glutathione and cysteinylglycine from a partial hydrolysate of glutathione

Investigation of the peptide AOD9604 in an ovine osteochondral defect model