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Clinical Recommendations Guidelines From Endocrinology Societies Major groups such as the American Thyroid Association and the Endocrine Society list no absolute contraindication for semaglutide in well-controlled thyroid diseaseunless there is a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

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The need for lifestyle changes in addition to medicine is also emphasized in the study as a key component of effective weight management

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