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Non-phosphorylated 4E-BP1 binds tightly to eukaryotic translation initiation factor 4E (eIF4E), a subunit of the eukaryotic initiation factor 4F complex responsible for mRNA cap binding, thereby inhibiting eIF4E-mediated initiation of protein synthesis (85)
First, zinc's effect on thyroid hormone conversion: zinc is required for the conversion of thyroxine (T4) to the active form triiodothyronine (T3) via deiodinase enzymes
This hormone plays a critical role in helping to regulate blood sugar and appetite
