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A recent pilot study revealed that both PWS and obese patients (n=8 and 11, respectively) who were administered a single 10-g exenatide injection or placebo in a single-blinded, crossover design showed increased satiety, lowered glucose level, and insulinotropic effects [8]
Its primary roles include regulating blood sugar and slowing digestion, playing a significant role in appetite control, satiety, and gastric emptying
However, it does suggest a biologically plausible reason some people report reduced urges related to alcohol, food, or other compulsive patterns
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