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2 associated with endometriosis
The explanatory variables in the model were randomized treatment (semaglutide or comparator), baseline CV risk score (from the CV risk prediction model derived from the LEADER data as described above) and the interaction between treatment and CV risk score
Diabetes - GLP-1 agonists should be primarily considered in patients with type 2 diabetes with suboptimal glycaemic control despite maximal tolerated dose of metformin (+/- other agents) especially where weight loss is desired and/or significant stroke risk is present
Many people require ongoing medication to maintain weight loss, as research shows significant weight regain when semaglutide is discontinued
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