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PMID: 2185038 The effect of some antineoplastic agents on glutathione S-transferase from human erythrocytes
5XFAD, 5XFAD Ppar-null , and 5XFAD Ppar-Hippo mice were aged 6 to 6.5 months at time of treatment and allowed to survive for another 46 weeks before they were sacrificed, and their brains were harvested for further analyses
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Ultrastructural analysis revealed that the mitochondrial ridge was reduced or absent and that rupture of the outer mitochondrial membrane (OMM) occurred in the Erastin-treated group and sh-GPX4 group(Fig
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