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The STEP trials for semaglutide showed average weight loss of about 14.9% over 68 weeks

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According to Boehringer Ingelheim's 2023 annual report, the drug's strong performance was attributed to continued strong momentum in indication growth, with European and US regulatory approvals for the treatment of chronic kidney disease and pediatric type 2 diabetes

The reduction in the flavoprotein MTHFR activity observed in individuals with the variant MTHFR 677TT genotype leads to an increase in plasma homocysteine (14)