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The dual agonist nature of tirzepatide, acting on both GIP and GLP-1 receptors, contributes to its efficacy in glycaemic control and weight management but also influences the gastrointestinal side effect profile
Of these, 47 participants in the semaglutide group and 46 participants in the placebo group completed the study
Watch for right upper quadrant pain, bloating after fatty meals, or fever, and discuss any concerning symptoms with your healthcare provider right away
It is important to contextualise these findings
GLP-1 therapy is often ideal for adults who: Struggle with ongoing weight gain or difficulty losing weight Have tried diets without long-term success Want a medically supervised program Have weight-related conditions such as insulin resistance, PCOS, or prediabetes These results are achieved gradually, safely, and under close medical supervision
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