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At the extreme end of this situation, where there is a genetic deficit in carnitine biosynthesis, some nasty stuff happens without carnitine supplementation [1]: Liver damage and dysfunction Brain damage Muscle weakness Lethargy Exercise intolerance Yet, there can also be situations of mild deficiency where these overt signs arent present

MELAS is not the result of a single gene defect and as such represents a constellation of related disorders that can result from defects in several of the mitochondrial genome encoded proteins of complex I

PubMed laboratory research record [PMID: 33466750] PubMed record related to this compound for laboratory literature review

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

The gap is in large-scale human randomised controlled trials, which have not yet been conducted