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Most people will experience indigestion at some point in their life
Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation
Fraud prevention and misuse detection have become more prominent as well
Anecdotal reports and clinical experience from obesity specialists often include notable back pain relief as one of the first changes patients notice within the first few months of GLP-1 therapy
(2024.) Fennel
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