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Modulation of oestrogen receptor signalling by association with the activated dioxin receptor

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Under unfolded protein stress conditions, GRP78 binds to unfolded or misfolded proteins and subsequently activates downstream ER stress sensors, including IRE1, PERK, and ATF6, to trigger a response to unfolded proteins (Yoboue et al., 2017) , (Wei et al., 2012)

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Naltrexone SR/Bupropion SR (Contrave): a new approach to weight loss in obese adults

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doi: 10.1038/srep16423 30 EbrahimiM.MousaviS

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