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Impact on End Product Pricing and Market Positioning SAG costs more per kilogram

Once the target dose is identified, we intend to study an implant at that dose over the full 6-month duration, over which our implant has already demonstrated encouraging results in preclinical animal models

J Biol Chem 281, 6489-6497

The primary concern relates not to direct drug interactions between most injectable GLP-1 agonists and levothyroxine, but rather to the potential impact on thyroid monitoring and the theoretical risk associated with thyroid C-cell tumours observed in animal studies

Liraglutide, however, has a faster adjustment period, with weekly dose increases for Saxenda and at least one week for Victoza