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The delay between glutathiones discovery in 1888 and its clinical use in the 1980s stems from three factors: poor oral bioavailability (the tripeptide was degraded in the gut before absorption), lack of understanding of its antioxidant mechanism until glutathione peroxidase was discovered in 1957, and institutional medicines slow adoption of redox biology as a treatment framework

If five or more days have passed, skip it and take the next dose on your regular day

The Challenge of Bioavailability If you have ever purchased a standard glutathione capsule from a grocery store, you might have been disappointed with the results

Occasionally taking your injection one day early is generally safe as long as at least 5 days have passed since your previous dose

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