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In bulls, a reduction in antioxidant activity was linked to decreased concentrations of polyunsaturated and unsaturated fatty acids, such as arachidonic and docosahexaenoic acid, making spermatozoa more susceptible to peroxidative damage in older individuals 6
Hypersensitivity reactions Severe allergic reactions are documented, presenting variously with rash, urticaria, angioedema, and anaphylaxis
Here are some of the key safety considerations and who should not take Zepbound: Thyroid Cancer Risk : Zepbound has a boxed warning (the most serious warning from the FDA) regarding the risk of thyroid C-cell tumors
Instruct patients to contact their healthcare provider if they have severe or persistent gastrointestinal symptoms [see Warnings and Precautions (5.7)] Hypersensitivity Reactions Inform patients that serious hypersensitivity reactions have been reported during postmarketing use of OZEMPIC
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