GLP-1 & tirzepatide bottom line: Prevent malnutrition, and muscle wasting is unlikely
These clinical trials were conducted separately under different protocols and patient populations, and results should not be compared directly
Int J Endocrinol 2012:717185 Dhillon-Smith RK, Tobias A, Smith PP, Middleton LJ, Sunner KK, Baker K, Farrell-Carver S, Bender-Atik R, Agrawal R, Bhatia K et al (2020) The prevalence of thyroid dysfunction and autoimmunity in women with history of miscarriage or subfertility
GLP-1 medications, on the other hand, may not be appropriate for people with a personal or family history of medullary thyroid carcinoma or MEN2, a history of pancreatitis, severe gastrointestinal conditions like gastroparesis, or anyone pregnant or breastfeeding
Insights into the Mechanism of Action of Tirzepatide: A Narrative Review