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Gene expression signatures of C1-27 and GSTO1 knockdown To identify pathways regulated by GSTO1 and to understand the mechanism of its antiproliferative effects, we used the nascent RNA Bru-seq method 27 to profile gene expression changes that occur in response to GSTO1 knockdown and inhibition
Sci Rep 6(1):21659 Schairer DO, Chouake JS, Kutner AJ, Makdisi J, Nosanchuk JD, Friedman AJ (2013) Evaluation of the antibiotic properties of glutathione
At the level of nucleotide synthesis, glutamine is the nitrogen donor for enzymes in the purine synthesis, including glutamine phosphoribosylpyrophosphate amidotransferase, phosphoribosyl formylglycinamidine synthetase, and guanosine monophosphate synthetase