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Despite this new evidence, further inconsistencies still remain in the field
It's listed in an FDA database as a generic drug that requires a prescription
MS.ID.001461
With developments in novel skin permeation enhancing methods such as microneedles and laser, copper compounds can potentially be used on skin for cosmeceutical or medicinal purposes 5,11,12
A 2022 study in the Journal of Cosmetic Dermatology found that subjects who applied L-ascorbic acid followed immediately by GHK-Cu experienced 40% higher transepidermal water loss (TEWL) and delayed barrier recovery compared to those who separated application by eight hours or more
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