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Secondly, we have shown that a neurotoxic product of TRP metabolism, 3-OHKY, predicts severity of clinical symptoms during the early phase of illness and before exposure to antipsychotic drugs ( Lastly, optimum levels of purine metabolites have been associated with the dynamics of clinical symptoms and therapeutic improvements, which may lead to discovery of novel targets for drug development
The receptor for the active form of vitamin D 3, 1,25(OH) 2 D(calcitriol), VDR, is a transcription factor regulating the expression of hundreds of genes
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