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In the Phase 2 clinical trial, participants generally met the following criteria: Body mass index (BMI) of 27 kg/m or above with at least one weight-related comorbidity (such as hypertension, dyslipidaemia, or obstructive sleep apnoea), or a BMI of 30 kg/m or above without comorbidities
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Additionally, semaglutide has been shown in experimental models to increase GPx activities and decrease lipid peroxidation (MDA levels) through the PI3K/Akt/Nrf2 signaling pathway (44)
He feels like the GLP-1 has helped him maintain more strength than he usually does in the slim-down phase before a big event
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