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In both groups the mean age and diseases duration resulted higher than the overall population of the main RCT studies [25, 26], which could derive from an older diabetic population in Italy than in other countries [27]
Determining the right dosage and frequency is crucial for achieving the best results
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Yamamoto H, Lee CE, Marcus JN, Williams TD, Overton JM, Lopez ME, Hollenberg AN, Baggio L, Saper CB, Drucker DJ, Elmquist JK
The time saved by skipping starting dose levels is typically lost to days spent managing severe nausea, missed doses from feeling too sick to inject, and sometimes complete protocol abandonment
In SARMOUNT 5 trials, tirzepatide reduced 20.2% of body weight while semaglutide reduced body weight by 13.7% after 72 weeks
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