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A cell under chronic oxidative bombardment sustains protein damage, mitochondrial DNA mutations, and lipid peroxidation

Acylcarnitine profile LCHAD, LCKAT and MTP deficiency are all characterized by accumulation of long-chain 3-hydroxyacylcarnitine species in DBS and plasma and cannot be separated from each other based on acylcarnitine profile [128]

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It remains unknown why this aggregation occurs

Figure 2 3.4 Correlations between S-5-HT and fatigue levels There was a negative correlation between S-5-HT and fatigue scores, such that increased serotonin levels were associated with reduced fatigue