Melanotan-2: The Shotgun Approach MT-2 hits the same MC1R receptor but also activates MC3R, MC4R, and MC5R : MC1R Melanin production (tanning) MC3R Energy homeostasis, cardiovascular function MC4R Sexual arousal, appetite regulation, erectile function MC5R Exocrine gland function, sebaceous secretion This non-selective binding is why MT-2 causes the "side effects" that many users actually seek out particularly the libido and appetite suppression effects
Here are some suggestions for managing common side effects: Headache and dizziness : Rest in a quiet and dark environment and ensure proper hydration
Common side effects of GLP-1/GIP include nausea, abdominal pain, dizziness, bloating, and belching
Viollet B, Guigas B, Sanz Garcia N, et al
J Nutr 126 : 16731682