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Significant weight loss from tirzepatide may reduce levothyroxine requirements in some patients, necessitating TSH monitoring at baseline, after substantial weight loss, and every 6-12 months once stable
The KLOW blend is an internal, systemic formulation
Important Notes: Both supplements need caution during pregnancy and nursing since safety data is limited
A common dysfunctional variant of ABCG2 (Q141K, rs2231142) significantly accelerates the onset of gout while delaying that of PD [25]
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