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Genuine B12 deficiency can contribute to anxiety-like symptoms, irritability, low mood, and a "wired but tired" feeling and correcting it can meaningfully improve how you feel
Read on for our expert guide to what to do if you skip a dose, and what to expect if youve taken a longer break
In a small secondary analysis, plasma anandamide changed differently across abstinence and continued-use groups, but the biomarker result does not establish withdrawal mechanisms or treatment targets
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