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[1] Whilst B12 supplementation is generally well-tolerated, some individuals report experiencing joint pain or aching after commencing treatment

doi: 10.1016/j.freeradbiomed.2018.02.009 112 WillisBCLieblerJMLuby-PhelpsKNicholsonAGCrandallEDDu BoisRMet al

Vegans, heavy drinkers, people over 50, and those on antacids face higher risk of B12 deficiency

When the researchers added NAC or a form of vitamin E to cultured human melanoma cells, they confirmed that the antioxidants improved the cells ability to move and invade a nearby membrane