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Some treatments can be risky, especially if done by untrained people or using unapproved drugs
However, plasma concentration of citrulline, synthesized in the small intestinal epithelium as part of the urea cycle and serving as a functional readout of IEC mitochondrial function, was decreased in ClpP IEC mice, in line with previous results from Hsp60 IEC mice (64) ( Figure 5D )
If switching the route of administration and dosage don't help, you may also have like a substrate issue
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