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This slow titration helps your body adjust and minimises side effects: 6 Weeks 1-4: 0.25 mg once weekly Weeks 5-8: 0.5 mg once weekly Weeks 9-12: 1.0 mg once weekly Weeks 13-16: 1.7 mg once weekly Week 17 onwards: 2.4 mg once weekly (maintenance dose) Practical tips for taking both medications Inject Wegovy on the same day each week, at any time of day, with or without food Continue taking metformin with meals as prescribed Stay well hydrated, especially if experiencing gastrointestinal side effects Eat smaller, more frequent meals if nausea is troublesome Limit ultra-processed food and take-aways Who should not combine Wegovy and metformin
Benowitz NL, Perez-Stable E, Fong I, Jacob P
This mechanism is key to understanding the 5-Amino-1MQ before and after effects
It is a pattern of eating that creates defined periods without caloric intake
But not everyone reacts the same way
