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Wilsons Disease or other copper metabolism disorders are absolute contraindications because the additional copper delivery could cause dangerous accumulation
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Unlike most peptides which degrade rapidly in stomach acid (pH 1.5-3.5), BPC-157 demonstrates remarkable acid stability, consistent with its derivation from a protein naturally active in gastric juice
All these contribute to reduced insulin sensitivity, IR, compensatory hyperinsulinaemia, metabolic abnormalities, and eventually T2D, creating a vicious cycle of feed-forward effect [1922]