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It is the most bioavailable form of B12, and also the most active, working mostly in our brains, nervous system, and liver (Lindstrand, 1964)
In the STEP 1 trial, semaglutide led to an average 14.9% reduction in body weight over 68 weeks , far outperforming placebo (NEJM study on semaglutide for weight loss)
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