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This anion then quickly breaks a disulfide bond (Cys58 - Cys63) and leads to Cys63's nucleophilically attacking the nearest sulfide unit in the GSSG molecule (promoted by His467), which creates a mixed disulfide bond (GS-Cys58) and a GS-anion
When combined with a GLP-1 receptor agonist, this may result in greater improvements in blood glucose and body weight
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Below, we discuss some of the potential effects
There are two commonly used experimental methods to investigate the characteristics of pain in rodents
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