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Their melanocytes need stronger, more sustained stimulation to switch from producing pheomelanin (red/yellow pigment) to eumelanin (brown/black pigment) (PubMed 17223853)
doi: 10.1210/jc.2012-3855 33 RonnJJensenEPWewer AlbrechtsenNJHolstJJSorensenCM
Patients with fair skin, blonde or red hair, blue or green eyes and a tendency to burn rather than tan are at heightened risk, as are those with a history of blistering sunburns in childhood
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