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IFN- can also activate CD8+ T cells and natural killer (NK) cells to produce perforin and granzymes, inducing programmed cell death of the infected target cells and destruction of the intracellular pathogen

[2] 10mg Vial Specifications Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val Molecular Formula: CHNO Molecular Weight: 1,419.5 Da Purity: 99% (third-party HPLC verified) Form: Lyophilized (freeze-dried) powder Vial Size: 10 mg Storage: 20 C (long-term)

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This warning was grounded on a wide number of studies reviewed in (Micallef et al., 2020b) including a recent report of the French Pharmacovigilance Network conducted in 2019 ( more topical than ever (Micallef et al., 2020b)