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It is secreted by enteroendocrine K-cells in the proximal small intestine in response to nutrient intake, particularly fats and carbohydrates

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In addition, post-treatment conception windows are heterogeneous, and the timing of treatment discontinuation relative to conception attempts is rarely standardized

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Table 2 Current knowledge on the role of miRNAs and lncRNAs on the GH/IGF1 axis and IGF system in osteosarcoma