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June 4, 2025 NAD+ (Nicotinamide Adenine Dinucleotide) A coenzyme and cofactor thats responsible for several cellular and biochemical processes within all living cells, NAD+ helps in various bodily functions: Protects DNA structure, reverses aging, preserves cells damage recovery processes, improves collagen production, maintains telomere length, promotes longevity in cellular health, reduces anxiety, increases glucose tolerance, repairs UV-damaged skin and helps avoid premature aging in skin

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The entire 4b helix shifts 1 in comparison to the 1EEM structure due to the sulfonamide group interacting with three residues (G128, V127 and P124) within the helix